Thermo Fisher Scientific HHATL/GUP1 Polyclonal Antibody
HHATL/GUP1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에서 반응하며 Protein A로 정제된 고순도 항체입니다. 연구용으로 Hedgehog 신호전달 관련 단백질 분석에 활용됩니다.
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Thermo Fisher Scientific HHATL/GUP1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human HHATL/GUP1 (amino acids 25–125) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
HHATL (Hedgehog Acyltransferase-Like) is a gene that codes for a protein involved in the regulation of Hedgehog signaling pathways. HHATL is located on chromosome 7q36.3. The encoded protein contains an acyltransferase domain, which mediates N-palmitoylation of the Sonic Hedgehog (Shh) protein—essential for proper signaling activity and distribution. HHATL is expressed in various tissues, notably in the heart, suggesting roles in cardiac development and function. Dysfunction in HHATL can disrupt Hedgehog signaling and affect developmental and cellular processes.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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