Thermo Fisher Scientific HYAL3 Polyclonal Antibody
Human HYAL3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer(40% glycerol 포함) 내 액상 형태로 제공. 세포 증식 및 분화 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HYAL3. Recombinant protein control fragment (Product # RP-96473) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642594 |
Product Specific Information
Immunogen sequence:
AAYQIHHSLR PGFAGPAVLD WEEWCPLWAG NWGRRRAYQA ASWAWAQQVF PDLDPQEQLY KAYTGFEQAA RALMEDTLRV AQALR
Sequence identity (orthologs):
- Mouse: 71%
- Rat: 77%
Target Information
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, a major glycosaminoglycan of the extracellular matrix. Regulated turnover of hyaluronan is crucial for biological processes such as cell proliferation, migration, and differentiation. The encoded protein may also play a role in sperm function.
This gene is located in the chromosome 3p21.3 region associated with tumor suppression, and expression of specific transcript variants may indicate tumor status. Alternatively spliced variants encoding multiple isoforms have been observed, some lacking hyaluronidase activity. This gene overlaps with N-acetyltransferase 6 (GCN5-related), sharing part of the first exon in some transcripts.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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