Thermo Fisher Scientific Neogenin Polyclonal Antibody
Thermo Fisher Scientific의 Neogenin Polyclonal Antibody는 인간 시료에 반응하는 토끼 유래 IgG 항체로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공하며, 장기 보관 시 -20°C에서 안정적 유지.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Neogenin. Recombinant protein control fragment (Product #RP-95257). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644617 |
Product Specific Information
Immunogen sequence:
SVNGSHKYKG NSKDVKPPDL WIHHERLELK PIDKSPDPNP IMTDTPIPRN SQDITPVDNS MDSNIHQRRN SYRGHESEDS MSTLAGR
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
The protein encoded by this gene mediates transcriptional control by interacting with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. It localizes to nuclear bodies and associates with chromatin and heterochromatin-associated factors. This protein belongs to the tripartite motif (TRIM) family, containing three zinc-binding domains (RING, B-box type 1, B-box type 2) and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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