
Thermo Fisher Scientific RING1 Monoclonal Antibody (OTI11G7), TrueMAB
RING1 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(P) 실험에 적합합니다. 인간 유래 단백질(aa 88-362)을 면역원으로 제작되었으며, 고순도의 액상 형태로 제공됩니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 88–362 of human RING1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex and interacts with the polycomb group proteins BMI1, EDR1, and CBX4. It colocalizes with these proteins in large nuclear domains and interacts with CBX4 via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, contiguous with the RING finger genes FABGL and HKE4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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