Thermo Fisher Scientific GABRG1 Polyclonal Antibody
Rabbit polyclonal antibody specific to human GABRG1 단백질 인식. IHC(P)에서 1:20~1:50 희석 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품. 신경전달 억제 관련 연구에 적합. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GABRG1. Recombinant protein control fragment (Product # RP-96574) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641815 |
Product Specific Information
Immunogen sequence:
RGVRLVFLLL TLHLGNCVDK ADDEDDEDLT VNKTWVLAPK IHEGDITQIL
Sequence identity:
- Mouse: 96%
- Rat: 94%
Target Information
Gabrg1 encodes a protein belonging to the ligand-gated ionic channel family. It is an integral membrane protein that inhibits neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel.
The Gabrg1 gene is clustered with three other family members on chromosome 4.
GABAA receptors, part of the Cys-loop family of ligand-gated ion channels, mediate the inhibitory effects of GABA along with GABAB receptors.
Structurally, Gabrg1 forms pentameric proteins consisting of five subunits from different families.
Diseases associated with GABRG1 include alcohol dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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