Thermo Fisher Scientific Mouse Prokineticin-2 Recombinant Protein, PeproTech

Applications

Tested Dilution

Publications

Functional Assay (Functional)

Assay-dependent

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Miscellaneous PubMed (Misc)

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View 1 publication 1 publication

Product Specifications

Species

Mouse

Published species

Mouse

Expression System

E. coli

Amino acid sequence

MAVITGACDK DSQCGGGMCC AVSIWVKSIR ICTPMGQVGD SCHPLTRKSH VANGRQERRR AKRRKRKKEV PFWGRRMHHT CPCLPGLACL RTSFNRFICL ARK

Molecular weight

11.6 kDa

Class

Recombinant

Type

Protein

Purity

≥ 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration

<1 EU/µg

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient

Product Specific Information

Recombinant Murine Prokineticin-2 is an 11.6 kDa protein consisting of 103 amino acid residues, including ten cysteine residues that can potentially form five pairs of intra-molecular disulfide bonds.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Target Information

Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.