Thermo Fisher Scientific DTYMK Recombinant Rabbit Monoclonal Antibody (JE64-08)
DTYMK 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. HEK293 세포에서 발현되었으며 Protein A로 정제되었습니다. DNA 합성 관련 연구용으로 사용되며, 장기 보관 시 -20°C에서 보관 권장.
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Thermo Fisher Scientific DTYMK Recombinant Rabbit Monoclonal Antibody (JE64-08)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE64-08 |
| Immunogen | Synthetic peptide within Human DTYMK aa 150–200/212 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931150 |
Target Information
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and serves as an intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), a chemotherapeutic drug used for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant (cdc8). DTYMK mRNA levels and enzyme activities are regulated by cell cycle and cell growth pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- MA5-44692_DTYMK_P23919-1_Rabbit.svg
- MA5-44692_DTYMK_P23919-1_Rabbit_PDP.jpeg
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