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Thermo Fisher Scientific GRK2 Polyclonal Antibody
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Thermo Fisher Scientific GRK2 Polyclonal Antibody

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GRK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. 고순도 Affinity chromatography 정제, PBS/glycerol buffer로 안정적이며 인간 GRK2에 반응합니다. 연구용 전용 제품입니다.

카탈로그번호
PA5144889
판매단위
pk
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마지막 업데이트 2025. 08. 01. 오후 10:24
Thermo Fisher Scientific PA5144889 GRK2 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
890,600원VAT 포함 979,660원

Thermo Fisher Scientific · Thermo Fisher Scientific GRK2 Polyclonal Antibody

Applications

Western Blot (WB)

  • Tested Dilution: 0.04–0.4 µg/mL

Immunocytochemistry (ICC/IF)

  • Tested Dilution: 0.25–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (Range: 640–689)
Conjugate Unconjugated
Form Liquid
Concentration 0.1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS (pH 7.2) with 40% glycerol
Contains 0.02% sodium azide
Storage Conditions Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles)
Shipping Conditions Wet ice
RRID AB_3092337

Product Specific Information

  • Immunogen sequence:
    LVQWKKELRD AYREAQQLVQ RVPKMKNKPR SPVVELSKVP LVQRGSANGL
  • Antigen sequence identity: Mouse 98%; Rat 98%

Target Information

ADRBK1 (GRK2) is a serine/threonine kinase involved in phosphorylation of G protein-coupled receptors (GPCRs). GRK2 (83 kDa) is ubiquitously expressed in mammals and regulates GPCR internalization and downstream signaling via beta-arrestin-1. Its activity is controlled by phosphorylation (PKC, Src, ERK1&2) and protein interactions. ERK-mediated phosphorylation at serine 670 inactivates GRK2 through negative feedback.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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