Thermo Fisher Scientific Vorsetuzumab Humanized Recombinant Human Monoclonal Antibody
Humanized recombinant monoclonal antibody targeting CD70 for research use; expressed in CHO cells and purified via Protein A; unconjugated liquid form with 2.68 mg/mL concentration; suitable for ELISA and other immunoassays; storage at -20°C recommended.
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Applications
- ELISA (assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human CD70 / TNFSF7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.68 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.5 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911124 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg (LAL method)
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Vorsetuzumab is a biosimilar antibody that targets CD70. The CD70 protein is a cytokine belonging to the TNF ligand family and acts as a ligand for TNFRSF27/CD27. It is expressed on activated, but not resting, T and B lymphocytes. CD70 promotes proliferation of costimulated T cells, enhances cytolytic T-cell generation, and contributes to T-cell activation. It also plays a role in B-cell activation, NK cell cytotoxic function, and immunoglobulin synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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