Thermo Fisher Scientific ALX3 Monoclonal Antibody (1F1)
Thermo Fisher Scientific의 ALX3 Monoclonal Antibody (1F1)는 인간 ALX3 단백질을 인식하는 Mouse IgM, kappa 형의 단일클론 항체입니다. Western blot 및 ELISA에 적합하며, 액상 형태로 제공됩니다. 연구용으로만 사용되며 -20°C에서 보관합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ALX3 Monoclonal Antibody (1F1)
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F1 |
| Immunogen | ALX3 (NP_006483, 150–249 a.a.) 부분 재조합 단백질 (GST tag 포함, GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KSKKRRNRTT FSTFQLEELE KVFQKTHYPD VYAREQLALR TDLTEARVQV WFQNRRAKWR KRERYGKIQE GRNPFTAAYD ISVLPRTDSH PQLQNSLWAG
Target Information
Aristaless-related genes are a group of paired-related homeobox genes which play a role in regulating vertebrate embryogenesis.
The homeodomain transcription factor aristaless-like 3 (ALX3) is expressed in mouse embryos from 8 days of gestation, predominantly in neural crest-derived mesenchyme and in lateral plate mesoderm. Expression analysis of human and mouse tissue reveals predominant ALX3 expression in brain tissue.
The Alx3 gene maps to chromosome 1p23-p13 and encodes a 343 amino acid protein. Preferential methylation of Alx3 occurs in advanced-stage neuroblastoma and may repress ALX3 expression. Treatment with the methylation inhibitor 5-aza-2'-deoxycytidine restores ALX3 expression.
Alx3 (-) mice lack a phenotype distinct from wild-type mice; however, Alx3/Alx4 double mutants demonstrate severe craniofacial abnormalities not present in Alx4 single mutants. Specifically, Alx3/Alx4 double mutant newborn mice have cleft nasal regions in addition to malformation of other neural crest-derived skull structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.