Thermo Fisher Scientific MEIOB Polyclonal Antibody
MEIOB 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간에 반응하며 Western blot에 적합. 합성 펩타이드 면역원으로 제조, 액상 형태, 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human MEIOB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690980 |
Product Specific Information
This target displays homology in the following species:
- Dog: 86%
- Horse: 93%
- Human: 100%
- Mouse: 86%
- Pig: 86%
- Rabbit: 77%
Target Information
Single-stranded DNA-binding protein required for homologous recombination in meiosis I.
Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis.
Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage.
May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination.
Displays single-stranded DNA 3′–5′ exonuclease activity in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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