Thermo Fisher Scientific COX5A Polyclonal Antibody
Rabbit polyclonal antibody against COX5A for WB applications. Detects endogenous COX5A in human, mouse, and rat samples. Supplied as a liquid, unconjugated antibody at 1 mg/mL. For research use only, not for diagnostic use.
- 카탈로그번호
- PA549920
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human COX5A (amino acids 37–57) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635373 |
Product Specific Information
This antibody detects endogenous levels of total COX5A protein.
Target Information
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that transfers electrons from cytochrome c to molecular oxygen, contributing to the proton electrochemical gradient across the inner mitochondrial membrane.
The complex consists of 13 mitochondrial- and nuclear-encoded subunits. Mitochondrially encoded subunits perform electron transfer and proton pumping, while nuclear-encoded subunits may regulate or assist in complex assembly.
The COX5A gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene, COX5AP1, is located on chromosome 14q22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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