Thermo Fisher Scientific TBL1XR1 Monoclonal Antibody (3G7)
Thermo Fisher Scientific의 TBL1XR1 Monoclonal Antibody (3G7)는 인간 TBL1XR1 단백질을 인식하는 Mouse IgG1 항체입니다. Western blot과 ELISA에 적합하며, 비결합형 액상 형태로 제공됩니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G7 |
| Immunogen | TBL1XR1 (NP_071347, 81 a.a. approximately 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LSLIDAVMPD VVQTRQQAYR DKLAQQQAAA AAAAAAAASQ QGSAKNGENT ANGEENGAHT IANNHTDMME VDGDVEIPPN KAVVLRGHES EVFICAWN
Target Information
Chromatin organization plays a fundamental role in regulating transcription in eukaryotic cells. The nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid hormone receptors (SMRT) play a role in diverse transcriptional repression pathways. N-CoR and SMRT each exist in large protein complexes, and are thought to mediate repression by recruiting histone deacetylases to generate repressive chromatin. HDAC3 is the main HDAC that associates with N-CoR and SMRT complexes, and its presence is essential for repression. TBLR1 is a WD-40 repeat protein that also associates with N-CoR and SMRT complexes, though its precise role remains to be elucidated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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