Thermo Fisher Scientific NPAT Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

CUT&RUN (C&R)

-

- -

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human NPAT. Recombinant protein control fragment (Product #RP-107495). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NPAT,uniProtId:Q14207-1,ncbiNodeId:9606,antigenRange:1027-1107,antigenLength:1427,antigenImageFileName:PA5-66839_NPAT_Q14207-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66839_NPAT_Q14207-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663287

Product Specific Information

Immunogen sequence: VSDKSIATDLG KKSEETTVPF PEESIVPAAK PCHRRVLCFD STTAPVANTQ GPNHKMVSQN KERNAVSFPN LDSPNVSSTL

Highest antigen sequence identity to the following orthologs - mouse 59%, rat 60%.

Target Information

Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.