Thermo Fisher Scientific JunD Polyclonal Antibody, Biotin
Drosophila Jun 단백질 특이적 Rabbit Polyclonal Antibody로, Biotin 결합 형태입니다. WB, IHC, ICC/IF, ELISA, IP 등 다양한 응용에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 세포 스트레스 반응 및 전사 조절 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Fruit fly |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to unique sequence on Drosophila melanogaster Jun protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
JunD is a transcription factor encoded by the JunD gene. Its transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N-terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family. Jun proteins can form dimers with Fos, ATF, and CREB family transcription factors to create the AP-1 complex, which regulates genes involved in cellular growth, proliferation, differentiation, and apoptosis. Additionally, JunD plays a key role in metabolism through modulation of the IGF-1 signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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