Thermo Fisher Scientific IYD Polyclonal Antibody
IYD 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. 인간 시료 반응성이 있으며, 고순도 친화 크로마토그래피 정제, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5100584
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IYD (Accession Q6PHW0), corresponding to amino acid residues R104–E154 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850092 |
Product Specific Information
Antibody detects endogenous levels of total IYD.
Target Information
This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor.
Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, also referred to as deiodinase deficiency or iodotyrosine dehalogenase deficiency.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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