Thermo Fisher Scientific Human Amyloid Precursor Protein Synthetic Peptide
인간 Amyloid Precursor Protein(APP) 근처 18개의 아미노산으로 구성된 합성 펩타이드입니다. APP 관련 항체의 블로킹 실험에 적합하며, Alzheimer 연구에 활용됩니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- PEP0826
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Amyloid Precursor Protein Synthetic Peptide
Thermo Fisher Scientific Human Amyloid Precursor Protein Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of human APP.
PEP-0826 can be used as a blocking peptide with polyclonal antibody PA5-20711.
Target Information
Amyloid Precursor Protein (APP) or Amyloid beta precursor protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
APP is important for neurite growth, neuronal adhesion, and axonogenesis. APP is a 100–140 kDa transmembrane glycoprotein that exists as several isoforms resulting from alternative splicing.
Proteolytic cleavage of APP by beta- and gamma-secretases generates beta amyloid, the primary component of senile plaques — a major histopathologic feature of Alzheimer’s disease.
Abnormal regulation and processing of APP also plays a role in Down’s syndrome, early onset familial Alzheimer’s disease, and cerebral hemorrhage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.