Thermo Fisher Scientific SYNPO2 Polyclonal Antibody
SYNPO2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P) 실험에 적합합니다. 사람, 생쥐, 랫트에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관하며, 연구용으로 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SYNPO2 (Accession Q9UMS6), corresponding to amino acid residues T626–V676 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853997 |
Product Specific Information
Antibody detects endogenous levels of total Synaptopodin.
Target Information
SYNPO2 (also known as myopodin) is a member of the synaptopodin family containing one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is located at the Z-disc. Under stress conditions, SYNPO2 translocates to the nucleus, suggesting a role in signaling pathways as well as structural organization. It binds to calmodulin, alpha-actinin, and smooth muscle myosin, stimulating actin polymerization in a calmodulin-dependent manner. Alterations in SYNPO2 expression have been associated with prostate cancer cell invasiveness and motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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