Thermo Fisher Scientific alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody (HL1692)
Human alpha Actinin 2 단백질을 인식하는 재조합 토끼 단일클론 항체로, WB, IHC, ICC 등 다양한 응용에 적합합니다. HEK293 세포에서 발현되었으며 Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody (HL1692)
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL1692 |
| Immunogen | Recombinant fragment of human alpha Actinin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093138 |
Target Information
Alpha actinins belong to the spectrin gene superfamily, which represents a diverse group of cytoskeletal proteins including alpha and beta spectrins and dystrophins.
Alpha actinin is an actin-binding protein with multiple roles in different cell types.
In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane.
In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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