Thermo Fisher Scientific Phospho-MEK3/MEK6 (Ser189, Ser207) Recombinant Rabbit Monoclonal Antibody (MKK3S189MKK6S207-D3)
Phospho-MEK3/MEK6 (Ser189, Ser207) 특이적 recombinant rabbit monoclonal antibody로, 인간 및 생쥐 시료에서 p38 MAP kinase 경로 연구에 적합. Western blot 및 Flow cytometry에 사용 가능하며, 높은 특이성과 로트 간 일관성을 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | 1–1,000 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MKK3S189MKK6S207-D3 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser189 of human phospho MKK3 and Ser207 of human phospho MKK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896989 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal production candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
This gene encodes a member of the dual specificity protein kinase family functioning as a mitogen-activated protein kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases, act as integration points for multiple biochemical signals.
This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress and participates in cellular processes such as stress-induced cell cycle arrest, transcription activation, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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