Thermo Fisher Scientific SULT2A1 Monoclonal Antibody (OTI1D2), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:2,000

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines and are selective toward phenols.
SULT2 enzymes prefer hydroxysteroids, while SULT3 family members are selective for N-substituted aryl and alicyclic compounds.
SULT2A1 catalyzes sulfonation of procarcinogen xenobiotics, hydroxysteroids, and bile acids, and is highly expressed in adrenal and liver tissues.
It plays a role in hepatic cholesterol homeostasis.
SULT2B1 consists of two isoforms (SULT2B1a and SULT2B1b), transcribed from the same gene by alternative splicing.
Both isoforms are selective for sulphation of 3β-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA, and androstenediol.
SULT2B1b is expressed in prostate, skin, placenta, and lung.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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