Thermo Fisher Scientific Insulin Monoclonal Antibody (1G11)
인슐린 단백질을 인식하는 마우스 모노클로날 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간 시료 반응성, Protein G 정제, 고농도(1 mg/mL) 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G11 |
| Immunogen | Recombinant human Insulin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, triglyceride formation, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide derived from proinsulin, which is cleaved post-translationally into peptide A and peptide B linked by two disulfide bonds and one molecule of C-peptide.
Deficiency of insulin results in diabetes mellitus, a major cause of morbidity and mortality. Insulin is also found in β-cell-derived tumors such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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