Thermo Fisher Scientific FASN Monoclonal Antibody (3B3-1D6)
FASN 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody. Western blot 및 ELISA에 적합하며, 고순도의 Affinity chromatography로 정제됨. PBS buffer에 보관, 보존제 미함유. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B3-1D6 |
| Immunogen | FASN (AAH07909, 1 a.a.–approximately 439 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MSTNDTIVSG TLPQRMASCL EVLDLFLNQP HMVLSSFVLA EKAAAYRDRD SQRDLVEAVA HILGIRDLAA VNLDSSLADL GLDSLMSVEV RQTLERELNL VLSVREVRQL TLRKLQELSS KADEASELAC PTPKEDGLAQ QQTQLNLRSL LVNPEGPTLM RLNSVQSSER PLFLVHPIEG STTVFHSLAS GLSIPTYGLQ CTRAAPLDSI HSLAAYYIDC IRQVQPEGPY RVAGYSYGAC VAFEMCSQLQ AQQSPAPTHN SLFLFDGSPT YVLAYTQSYR AKLTPGCEAE AETEAICFFV QQFTDMEHNR VLEALLPLKG LEERVAAAVD LIIKSHQGLD RQELSFAARS FYYKLRAAEQ YTPKAKYHGN VMLLRAKTGG AYGEDLGADY NLSQVCDGKV SVHVIEGDHR TLLEGSGLES IISIIHSSLA EPRVSVREG
Target Information
Fatty acid synthase (FASN) is a multifunctional protein that catalyzes the synthesis of palmitate from acetyl-CoA and malonyl-CoA in the presence of NADPH, producing long-chain saturated fatty acids. In certain cancer cell lines, FASN has been found fused with estrogen receptor-alpha (ER-alpha), where the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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