Thermo Fisher Scientific MTF2 Polyclonal Antibody
MTF2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응하며 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관됩니다. 줄기세포 분화 및 PRC2 복합체 연구에 활용 가능합니다.
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Thermo Fisher Scientific MTF2 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MTF2. Recombinant protein control fragment (Product #RP-107670) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665243 |
Product Specific Information
- Immunogen sequence:
GRTEGTAHSSN TSDVDFTGAS SAKETTSSSI SRHYGLSDSR KRTRTGRSWP AAIPHLRRRR GRLPRRALQT QNSEIVKDDE - Ortholog sequence identity: Mouse 93%, Rat 93%
Target Information
Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at Lys-36 (H3K36me3) and recruits the PRC2 complex.
Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting PRC2, enhancing H3K27me3 methylation activity.
Regulates transcriptional networks during embryonic stem cell self-renewal and differentiation.
Promotes PRC2 recruitment to the inactive X chromosome and target genes in ES cells.
Required for repression of Hox genes via enhanced H3K27me3 methylation.
May inhibit PRC2 activity under certain conditions, activating CDKN2A gene and promoting cellular senescence.
Binds to the metal-regulating-element (MRE) of the MT1A gene promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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