Thermo Fisher Scientific SLC6A4 Polyclonal Antibody
SLC6A4 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간·마우스·랫트 시료에 반응합니다. IHC 및 IHC(P)에서 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (IHC)
Tested dilution: –
View 1 publicationImmunohistochemistry (Paraffin) (IHC (P))
Tested dilution: 1:25–1:100
–
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 6 (neurotransmitter transporter), member 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636077 |
Product Specific Information
The antibody detects endogenous levels of total SLC6A4 / 5-HTT protein.
Target Information
SERT (SLC6A4) is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. It terminates serotonin action and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants such as amphetamines and cocaine and belongs to the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter region of this gene affects serotonin uptake rate and may be associated with sudden infant death syndrome, aggressive behavior in Alzheimer’s disease, and depression susceptibility following emotional trauma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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