Thermo Fisher Scientific ACAT2 Recombinant Rabbit Monoclonal Antibody (JE58-83)
ACAT2 단백질을 인식하는 토끼 단클론 항체로 Western blot, IHC, Flow Cytometry에 적합. 인간, 마우스, 랫트 반응성. HEK293 발현 시스템에서 제조된 재조합 항체로 높은 특이성과 재현성을 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE58-83 |
| Immunogen | Recombinant protein within human ACAT2 aa 198–397/397 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931344 |
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins that act as receptors for Wnt signaling proteins.
The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains.
Unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif.
It functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting oncogenic transformation, cell proliferation, and apoptosis suppression.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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