Thermo Fisher Scientific 4EBP1 Polyclonal Antibody
Thermo Fisher Scientific의 4EBP1 Polyclonal Antibody는 인간 4EBP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 분석에 적합합니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, PBS buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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- PA511830
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 48–77 of human EIF4EBP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11004510 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
This gene encodes a member of the translation repressor protein family. The protein interacts directly with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction with eIF4E inhibits complex assembly and represses translation. The protein is phosphorylated in response to signals such as UV irradiation and insulin, leading to dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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