Thermo Fisher Scientific Cytokeratin Pan Type II Polyclonal Antibody
Rabbit polyclonal antibody recognizing Cytokeratin Pan Type II (human KRT2). Suitable for Western blot applications at 1:1,000–1:3,000 dilution. Affinity-purified, liquid form, 1 mg/mL concentration. Stored at -20°C in PBS with 50% glycerol and 0.02% s...
- 카탈로그번호
- PA5103456
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KRT2 (Accession P35908), corresponding to amino acid residues C3–F53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852794 |
Product Specific Information
This antibody detects endogenous levels of total Cytokeratin 2e.
Target Information
Cytokeratin pan belongs to a subfamily of intermediate filament proteins characterized by remarkable biochemical diversity. In human epithelial tissues, at least 20 different cytokeratin polypeptides are expressed, ranging in molecular weight from 40 to 68 kDa and isoelectric points between 4.9 and 7.8.
Individual cytokeratins (numbered 1–20) are expressed depending on epithelial type and differentiation stage. Cytokeratin subtype expression patterns assist in distinguishing epithelial malignancies and are valuable in tumor diagnosis using immunohistochemistry, cytopathology, and flow cytometry.
Their expression varies with cell type, differentiation stage, growth environment, and disease state. Keratins are widely used as markers in cancer research and diagnostic studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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