Thermo Fisher Scientific GLP2R Polyclonal Antibody
GLP2R 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 및 영장류 시료에 반응합니다. IHC(P) 분석에 적합하며 Proteinase K 항원 회복을 권장합니다. 항원 친화 크로마토그래피로 정제되었고, 1 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1.25–2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human GLP2R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550243 |
Product Specific Information
- In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
- Percent identity with other species by BLAST analysis:
- Human, Monkey, Marmoset: 100%
- Gorilla, Gibbon: 94%
- Rat, Dog, Bovine, Elephant, Panda: 81%
Target Information
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor and GLP1 receptor.
Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like GLP1 and glucagon, it is derived from the proglucagon peptide encoded by the GCG gene.
GLP2 stimulates intestinal growth and increases villus height in the small intestine, with increased crypt cell proliferation and decreased enterocyte apoptosis. It also prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R is expressed in the gut and is closely related to the glucagon receptor (GCGR) and GLP1 receptor (GLP1R).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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