Thermo Fisher Scientific NeuroD1 Polyclonal Antibody
NeuroD1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 검증 완료. 인간, 생쥐, 랫트 반응성. KLH 결합 합성 펩타이드 면역원 사용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 318–348 amino acids from the C-terminal region of human NeuroD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Size-exclusion - Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2149214 |
Target Information
NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It binds to the insulin gene E-box, and efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein.
Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6), a form of non-insulin-dependent diabetes mellitus characterized by autosomal dominant inheritance, onset during young adulthood, and a primary defect in insulin secretion.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-11889_NeuroD1_Q13562-1_Rabbit.svg
- PA5-11889_NeuroD1_Q13562-1_Rabbit_PDP.jpeg
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