Thermo Fisher Scientific CD148 Monoclonal Antibody (MEM-CD148/05), PE
CD148 단백질의 세포 표면 발현을 검출하는 PE 결합 단일클론 항체. 인간 시료에 반응하며 Flow Cytometry에 적합. IgG2b 아이소타입으로 제작되어 높은 특이성과 재현성을 제공. 4°C 암소 보관, 동결 금지.
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Applications
- Flow Cytometry (Flow): 10 µL/1×10⁶ cells
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-CD148/05 |
| Immunogen | Human recombinant CD148 (amino acids 1–444) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534577 |
Available Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD148, a highly glycosylated (up to 250 kDa) receptor-like protein tyrosine phosphatase expressed mainly in lymphocytes, myeloid cells, and epithelial cells.
Target Information
CD148 is a highly glycosylated transmembrane protein (~250 kDa) containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region. Expression is found on fibroblasts, epithelial cells, lymphocytes (B, T, NK cells), and myeloid cells (monocytes, granulocytes). CD148 can dephosphorylate proteins such as LAT and PLC-γ, playing a role in the downregulation of T cell activation. Expression can be upregulated following T cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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