Thermo Fisher Scientific Parvalbumin Polyclonal Antibody
Parvalbumin 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 근육 및 신경 세포 내 칼슘 결합 단백질 연구에 유용하며, 동결 건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:200–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse Parvalbumin alpha (Pva) conjugated to blue carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Parvalbumin alpha.
Target Information
Parvalbumin (PV) is a calcium-binding protein expressed in specific muscle fibers and fast-firing neurons. It belongs to the EF-hand protein family and plays a role in calcium decay during the contraction/relaxation cycle of fast-twitch muscles. The concentration of parvalbumin correlates with the rate of muscle relaxation.
PV is also expressed in a subset of GABAergic interneurons that help maintain the balance between excitation and inhibition in the cortex and hippocampus. In amyotrophic lateral sclerosis (ALS) patients, PV immunoreactivity is absent from neuron populations lost early in the disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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