Thermo Fisher Scientific RHD Monoclonal Antibody (C1)
RHD 단백질을 인식하는 Mouse monoclonal antibody (Clone C1). Western blot, IHC(P), ICC/IF에 적합하며 Human 및 Pig 시료 반응. Protein A/G 정제, 1 mg/mL 농도, PBS/glycerol buffer 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1 |
| Immunogen | Recombinant Human RHD protein, Ser2–Gly87 (Accession #Q02161) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090576 |
Target Information
The Rhesus (Rh) blood group system is one of the most complex and important systems in humans. Two highly homologous genes, RHD and RHCE (collectively referred to as RH30 or RHCED), encode the antigens of the Rh blood group system. These genes map to human chromosomal position 1p34.1–1p36.
The RHD gene, often deleted in a large segment of the population, encodes the most potent blood group immunogen, the D antigen. Rh incompatibility between maternal and fetal blood types can result in hemolytic disease of the newborn (HDN).
The RHCE gene exists in four allelic forms, determining expression of Ce, ce, cE, or CE antigen combinations. RHCED antigens are integral membrane proteins with 12 transmembrane helices, maintaining erythrocyte membrane integrity. Rh antigenic activity requires complex formation between RHCED antigens and RHAG (RH50).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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