Thermo Fisher Scientific H3K64ac Polyclonal Antibody
Human Histone H3에서 유래한 합성 펩타이드 항원을 이용한 Rabbit Polyclonal 항체. ICC/IF 및 ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:10–1:100 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from Human Histone H3.1 protein (59–70aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.12 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_2914956 |
Product Specific Information
Antibody tested in Indirect ELISA.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translationally, histones are modified in various ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several types of post-translational modification that influence cellular processes, including methylation, acetylation, and phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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