Thermo Fisher Scientific GNB5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GNB5 protein. Recognizes a unique peptide sequence within the D1 blade region. Suitable for research use in studying G protein signaling. Supplied as liquid, unconjugated form. Store at 4°C short term or -20°C...
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Thermo Fisher Scientific GNB5 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GNB5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642083 |
Product Specific Information
Immunogen sequence:
TFLVNVFGSC DKCFKQRALR PVFKKSQQLS YCSTCAEIMA TEGLHENETL ASLKSEAESL KGKLEEERAK LHDVELHQVA ERVEALGQFV MKTRRTLKGH GNKVLCM
Sequence identity to orthologs:
- Mouse: 98%
- Rat: 64%
Target Information
The Gb5 protein is a G protein subunit predominantly expressed in the central nervous system. Two forms are observed: one in the brain (39 kDa) and one in the retina (44 kDa). Gb5 forms tight complexes with RGS7, a regulator of G protein signaling, localized to most brain regions. Gb1–4 do not colocalize with RGS7 despite similar neuronal distribution.
This antibody specifically recognizes a peptide sequence within the D1 blade region, not found in Gb1–4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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