Thermo Fisher Scientific Cytokeratin 14 Polyclonal Antibody
Rabbit polyclonal antibody against human Cytokeratin 14 for WB and IHC applications. Recombinant protein immunogen ensures high specificity. Suitable for epithelial and carcinoma marker studies. Supplied as liquid, unconjugated form, 0.1 mg/mL concentr...
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- PA5110884
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Cytokeratin 14 (Product #RP-93527) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856295 |
Product Specific Information
Immunogen sequence:
TYRRLLEGED AHLSSSQFSS GSQSSRDVTS SSRQIRTKVM DVHDGKVVST HEQVLRTKN
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs are identified, classified as type I (acidic polypeptides) or type II (basic polypeptides).
Keratin 14 belongs to the type I subfamily of low molecular weight keratins and pairs with keratin 5. It distinguishes stratified epithelial cells from simple epithelial cells and is useful for identifying squamous cell carcinomas. It also serves as a prognostic marker in breast carcinomas.
At least one member of the acidic family and one of the basic family is expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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