Thermo Fisher Scientific HTR3B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human HTR3B. Recombinant protein control fragment (Product #RP-95652). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HTR3B,uniProtId:O95264-1,ncbiNodeId:9606,antigenRange:339-411,antigenLength:441,antigenImageFileName:PA5-58838_HTR3B_O95264-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58838_HTR3B_O95264-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642585

Product Specific Information

Immunogen sequence: FLCLRGDTDA DRPRVEPRAQ RAVVTESSLY GEHLAQPGTL KEVWSQLQSI SNYLQTQDQT DQQEAEWLVL LSR

Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 51%.

Target Information

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.