Thermo Fisher Scientific PIP5K1C Polyclonal Antibody, MaxPab
PIP5K1C 단백질을 인식하는 토끼 폴리클로날 항체로, Western Blot에 적합합니다. 인간 단백질에 반응하며, PBS(pH 7.4) 용액 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PIP5K1C Polyclonal Antibody, MaxPab
Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | PIP5K1C (AAH11138.1, 1 a.a. ~ 206 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MTPRHPLFTS RRPPAQPTRC ARKAPAVEKP DPSPRSPART HTPREQPLHS AQERGRPSSG TGQPRGSQHP SGQAHVGSSL RAQRVCPALG SDLGLSSQPG AHLLAPGIHP SAPALSLRRT PSRHPPGRQG QRSEGVSGTW MASRDRGIVI SKAQPPEATP VLPGSPRVAL PRALAPETPR ACGVTRSSRC GPGRAAPRPG QPPSAE
Target Information
PIP5K1C lipid kinase, also known as phosphatidylinositol-4-phosphate 5-kinase 1 gamma, phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate.
PIP5K1C is localized at synapses and plays roles in endocytosis and cell migration. It directly associates with β-catenin and enhances β-catenin activity downstream of growth factor stimulation.
PIP5K1C expression and kinase activity promote β-catenin phosphorylation on residues that facilitate nuclear import and transcriptional activity.
Deficiency in PIP5K1C impairs neutrophil recruitment due to defective adhesion, regulating adhesion through RhoA GTPase and integrin activation by chemoattractants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.