Thermo Fisher Scientific KPNA2 Polyclonal Antibody
KPNA2 단백질을 인식하는 Thermo Fisher Scientific의 염소 다클론 항체입니다. Western blot 및 면역세포화학(ICC/IF)에 사용됩니다. 핵 단백질 수입 과정 연구에 적합하며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.03–0.1 µg/mL | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence QVQDGAPGTFNF, from C Terminus of the protein sequence according to NP_002257 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2133674 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX26036-PEP).
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The import of proteins into the nucleus is a process that involves at least two steps:
- Energy-independent docking of the protein to the nuclear envelope.
- Energy-dependent translocation through the nuclear pore complex.
Imported proteins require a nuclear localization sequence (NLS), which generally consists of a short region of basic amino acids or two such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import include the Xenopus protein importin and its yeast homolog SRP1, which bind to the NLS.
KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in VJ recombination.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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