Thermo Fisher Scientific DMRT1 Monoclonal Antibody (1G11)
DMRT1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 1G11). Western blot 및 ELISA에 적합하며, 인간 시료에 반응. Affinity chromatography로 정제된 액상 항체로, PBS(pH 7.4)에 보존제 없이 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G11 |
| Immunogen | DMRT1 (AAH40847.1, 1 a.a. – approximately 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MPNDEAFSKP STPSEAPHAP GVPPQGRAGG FGKASGALVG AASGSSAGGS SRGGGSGSGA
SDLGAGSKKS PRLPKCARCR NHGYASPLKG HKRFCMWRDC QCKKCNLIAE RQRVMAAQVA
LRRQQAQEEE LGISHPIPLP SAAELLVKRE NNGSNPCLMT ECSGTSQPPP ASVPTTAASE
GRMVIQDIPA VTSRGHVENT PDLVSDSTYY SSFYQPSLFP YYNNLYNCPQ YSMALAADSA
SGEVGNPLGG SPVKNSLRGL PGPYVPGQTG NQWQMKNMEN RHAMSSQYRM HSYYPPPSYL
GQSVPQFFTF EDAPSYPEAR ASVFSPPSSQ DSGLVSLSSS SPISNKSTKA VLECEPASEP
SSFTVTPVIE EDETarget Information
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain).
The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway and a key regulator of male development in flies and nematodes.
This gene exhibits a gonad-specific and sexually dimorphic expression pattern.
Defective testicular development and XY feminization occur when this gene is hemizygous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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