Thermo Fisher Scientific MRCK alpha Polyclonal Antibody
Thermo Fisher Scientific의 MRCK alpha Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 Rabbit IgG 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 합성 펩타이드를 면역원으로 사용했습니다. 액상 형태로 -20°C에서 보관합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:30–1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human MRCK alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.6 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2692236 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
CDC42BPA (MRCKA) is a serine/threonine kinase involved in actin cytoskeleton assembly and organization.
Three independent coiled-coil domains and the N-terminal region preceding the kinase domain mediate intermolecular interactions leading to MRCK alpha multimerization.
Transautophosphorylation is critical for regulating MRCK alpha catalytic activity.
Binding of phorbol esters releases autoinhibition, enabling N-terminal dimerization and kinase activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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