Thermo Fisher Scientific PP2A-alpha Polyclonal Antibody
PP2A-alpha 단백질 인산화 조절 연구용 폴리클로날 항체. Western blot, IHC, ELISA, IP에 적합하며 인간, 설치류 등 다양한 종에 반응. 합성 펩타이드 면역원 사용, Affinity chromatography로 정제된 고순도 항체. 연구 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 410–486 of human Serine/Threonine-Protein Phosphatase 2A, B56-Alpha subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In eukaryotes, phosphorylation and dephosphorylation of proteins on serine and threonine residues are essential mechanisms regulating cellular functions such as division, homeostasis, and apoptosis. Protein phosphatases play a key role in these processes. The protein phosphatase (PP) holoenzyme is typically a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified: PP1, PP2A, PP2B (calcineurin), and PP2C. The PP2A family includes PP2A alpha and PP2A beta subfamily members. Another catalytic subunit, PPX (also known as PP4), is considered part of a novel PP family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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