Thermo Fisher Scientific TAS2R1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human TAS2R1(Accession Q9NYW7), corresponding to amino acid residues A13-F63. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TAS2R1,uniProtId:Q9NYW7-1,ncbiNodeId:9606,antigenRange:13-63,antigenLength:299,antigenImageFileName:PA5-102255_TAS2R1_Q9NYW7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-102255_TAS2R1_Q9NYW7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2851669

Product Specific Information

Antibody detects endogenous levels of total TAS2R1.

Target Information

The sense of taste is essential for the survival of organisms. For example, the ability to identify sweet-tasting foods enables animals to seek out food with high nutritive value, whereas the ability to identify bitter substances enables them to avoid the ingestion of potentially harmful substances. A family of integral membrane proteins are involved in taste perception and include T1R, which is involved in sweet taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Specifically, T2R1 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.