Thermo Fisher Scientific MYH7 Polyclonal Antibody
Rabbit polyclonal antibody targeting MYH7 for IHC and ICC applications. Reacts with human and mouse MYH7. Affinity purified, supplied in PBS with sucrose and sodium azide. Suitable for research on cardiac and skeletal muscle proteins.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse MYH7 (aa 215–264) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688385 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%.
Target Information
Muscle myosin is a hexameric protein composed of two heavy chain subunits, two alkali light chain subunits, and two regulatory light chain subunits.
The MYH7 gene encodes the beta (or slow) heavy chain subunit of cardiac myosin, predominantly expressed in the human ventricle and in slow-twitch skeletal muscle fibers.
Expression levels of MYH7 correlate with cardiac muscle contractile velocity and are altered under thyroid hormone depletion or hemodynamic overload.
Mutations in MYH7 are linked to familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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