Thermo Fisher Scientific COG8 Polyclonal Antibody
Human COG8 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. COG 복합체 연구 및 Golgi 관련 단백질 분석에 적합.
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- pk
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COG8. Recombinant protein control fragment (Product #RP-98595) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640007 |
Product Specific Information
Immunogen sequence:
AFANYKTFIR GAECTERIHR LFGDVEASLG RLLDRLPSFQ QSCRNFVKEA EEISSNRRMN SLTLNRHTEI LEILEIPQLM D
Antigen sequence identity:
- Mouse: 96%
- Rat: 98%
Target Information
The COG8 gene encodes a protein that is part of the conserved oligomeric Golgi (COG) complex. This multiprotein complex plays a structural role in the Golgi apparatus and participates in intracellular membrane trafficking and glycoprotein modification.
Mutations in this gene cause congenital disorder of glycosylation, type IIh, characterized by under-glycosylated serum proteins and symptoms such as severe psychomotor retardation, failure to thrive, seizures, and intolerance to dairy and wheat products.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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