Thermo Fisher Scientific SLC19A1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 452-591 of human SLC19A1 (NP_9192311) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC19A1,uniProtId:P41440-1,ncbiNodeId:9606,antigenRange:452-591,antigenLength:591,antigenImageFileName:PA5-88778_SLC19A1_P41440-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88778_SLC19A1_P41440-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805125

Product Specific Information

Immunogen sequence: LDGLRHCQRG HHPRQPPAQG LRSAAEEKAA QALSVQDKGL GGLQPAQSPP LSPEDSLGAV GPASLEQRQS DPYLAQAPAP QAAEFLSPVT TPSPCTLCSA QASGPEAADE TCPQLAVHPP GVSKLGLQCL PSDGVQNVNQ; Positive Samples: HeLa, U-87MG; Cellular Location: Membrane, Multi-pass membrane protein

Target Information

Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.