Thermo Fisher Scientific CHRNA10 Polyclonal Antibody
CHRNA10 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB 및 ICC/IF에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도 친화 크로마토그래피로 정제되었습니다. 청각 자극 조절 관련 연구용으로 사용됩니다.
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Thermo Fisher Scientific CHRNA10 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CHRNA10 (Accession Q9GZZ6), corresponding to amino acid residues A394–L444 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851149 |
Product Specific Information
This antibody detects endogenous levels of total CHRNA10.
Target Information
CHRNA10 is an ionotropic receptor involved in the modulation of auditory stimuli. Agonist binding induces conformational changes that open an ion-conducting channel across the plasma membrane. The channel is permeable to divalent cations, including calcium, which may activate a potassium current leading to membrane hyperpolarization. In the ear, this mechanism can reduce basilar membrane motion, alter auditory nerve activity, and protect against acoustic trauma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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