Thermo Fisher Scientific OMA1 Polyclonal Antibody
Human OMA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 SPR에 사용 가능. 합성 펩타이드 면역원 기반, 고순도 친화 크로마토그래피 정제. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific OMA1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Surface Plasmon Resonance (SPR) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human OMA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884490 |
Product Specific Information
- Immunogen sequence: WAICPRDSLA LLCQWIQSKL QEYMFNRPYS RKLEAEADKI GLLLAAKACA
- Storage guidance:
- Short term use: Store at 2–8°C up to 1 week
- Long term storage: Store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology:
Cow: 85%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 86%; Rat: 86%; Yeast: 83%; Zebrafish: 85%
Target Information
OMA1 (Overlapping with the m-AAA protease 1 homolog) is also known as MPRP1 (Metalloprotease-related protein 1) and belongs to the peptidase M48 family.
It is a zinc metalloprotease that spans the inner mitochondrial membrane with several predicted transmembrane domains. The 60 kDa form of OMA1 rapidly accumulates concomitantly with the cleavage of all OPA1 variants, while the 40 kDa form may represent the inactive enzyme, and the 60 kDa form the active one.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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