Thermo Fisher Scientific OMA1 Polyclonal Antibody

Thermo Fisher Scientific OMA1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Immunogen sequence: WAICPRDSLA LLCQWIQSKL QEYMFNRPYS RKLEAEADKI GLLLAAKACA
• Storage guidance:
  • Short term use: Store at 2–8°C up to 1 week
  • Long term storage: Store at -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  Cow: 85%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 86%; Rat: 86%; Yeast: 83%; Zebrafish: 85%

Target Information

OMA1 (Overlapping with the m-AAA protease 1 homolog) is also known as MPRP1 (Metalloprotease-related protein 1) and belongs to the peptidase M48 family.
It is a zinc metalloprotease that spans the inner mitochondrial membrane with several predicted transmembrane domains. The 60 kDa form of OMA1 rapidly accumulates concomitantly with the cleavage of all OPA1 variants, while the 40 kDa form may represent the inactive enzyme, and the 60 kDa form the active one.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.