Thermo Fisher Scientific TBC1D17 Polyclonal Antibody
TBC1D17 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 마우스에서 반응하며, 합성 펩타이드로 면역화되었습니다. 액상 형태, 0.5 mg/mL 농도, 친화 크로마토그래피로 정제되었습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of mouse TBC1D17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2689989 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%; Dog: 93%; Goat: 80%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%; Zebrafish: 77%
Target Information
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR), and reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC).
Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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