Thermo Fisher Scientific PPM1E Polyclonal Antibody
Human PPM1E 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200–1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로 CaM kinase 관련 신호전달 연구에 적합.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPM1E. Recombinant protein control fragment (Product # RP-91580) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645832 |
Product Specific Information
- Immunogen sequence:
TVIVVFLRDM NKAVNVSEES DWTENSFQGG QEDGGDDKEN HGECKRPWPQ HQCSAPADLG YDGRVDSFTD RTSLSPGSQI NVLE - Highest antigen sequence identity:
- Mouse: 95%
- Rat: 98%
Target Information
Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2.
Dephosphorylates and inactivates PAK.
May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42.
Dephosphorylates PRKAA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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